Time-resolved Fluorescence Spectroscopy

April 15, 2009

PicoQuants 7th Short Course on Principles and Applications of Time-resolved Fluorescence Spectroscopy, taking place from Nov. 9-12, 2009, in Berlin, Germany is intended for individuals wishing an introduction of the basics of fluorescence spectroscopy and its applications to the Life Sciences. The course is held in cooperation with Dr. J.R. Lakowicz from the Center of Fluorescence Spectroscopy (CFS) in Baltimore. It will focus on time-resolved spectroscopy applications (i.e. measurements on bulk samples). Registration deadline is Aug. 31, 2009.
www.picoquant.com/_trfcourse.htm


Workshop on Single Molecule Spectroscopy

März 26, 2009

For the 15th time now, PicoQuant is hosting the International Workshop on Single Molecule Spectroscopy and Ultrasensitive Analysis in the Life Sciences. The workshop will take place from Sep. 15-18, 2009 in Berlin-Adlershof, WISTA campus, Germany. Topics that will be covered during the talks and a poster session are: Fluorescence Lifetime Correlation Spectroscopy (FLCS), Pulsed Interleaved Excitation (PIE) and Stimulated Emission Depletion Spectroscopy (STED), two-photon excitation, new and robust fluorophores such as quantum dots, metalfluorophore interactions, analysis of living cells, investigation of protein folding and biological function studies of macromolecules and Foerster Resonance Energy Transfer (FRET).
www.picoquant.com/_workshop.htm


European Biophysics Congress

März 24, 2009

The 7th European Biophysics Congress will take place in Genoa, Italy from July 11-15, 2009. The congress is organized on behalf of the Italian Society of Pure and Applied Biophysics (SIBPA) and the European Biophysics Societies Association (EBSA). It address to representatives from academic and industrial institutions.

Conference topics include:

1. Single molecule biophysics
2. Lipid biophysics
3. Folding/unfolding of proteins
4. Multiscale simulation
5. Chromatin, nucleosomes and molecular machines
6. Glycobiophysics
7. Biomolecular self-assembly
8. Photosensory biophysics
9. Structure-function relationships (channels, pumps, exchangers)
10. Live cell imaging
11. Protein-ligand interactions
12. Membrane microdomains and signalling
13. Biological motility and molecular motors
14. Interaction and recognition of DNA
15. Biomaterials and drug delivery
16. Single molecule fluorescence
17. Imaging and spectroscopy
18. Fluorescent proteins
19. Solar energy conversion and photosynthesis
20. Statistical, soft matter and biological physics
21. Condensed colloidal phase in biology
22. Ion channels in channelopathies and cancer
23. RNA world
24. Stem cells

www.ebsa2009.org

biophysics-congress-genova


Improving Drug Design

März 6, 2009

The Commonwealth Scientific and Industrial Research Organisation (CSIRO) has patented an improved microscopy method for measuring proteins to help scientists creating new pharmaceuticals for targeted proteins. The method, called Differential Aberration Correction (DAC) microscopy, measures distances at the molecular level in two and three dimensions using conventional fluorescence microscopy.

The leader of CSIRO’s Biotech Imaging team, Dr. Pascal Vallotton, says DAC microscopy measures distances a million times smaller than a tape measure can – in nanometers rather than millimeters. “We want to use our technique to measure accurate dimensions of proteins called membrane receptors. These proteins sit on cell boundaries, acting as gate-keepers, and they represent a class of biomolecules targeted by over 50% of pharmaceuticals”, he says. DAC microscopy is an improvement on an older technology, called FRET. Compared to FRET, DAC measures 1-250 nanometers, giving a more complete picture of drug-membrane receptor interactions. It will complement other techniques like X-ray crystallography. The DAC software was recently demonstrated in the US and will be presented at the Society for Biomolecular Screening conference in Lilles, France in April.
www.csiro.au

Fluorescence microscopy image of 100nm microspheres used to develop the DAC microscopy method.

Fluorescence microscopy image of 100nm microspheres used to develop the DAC microscopy method.


Focus on Microscopy 2009

Januar 9, 2009

From Sunday April 5 to Wednesday April 8, 2009 the Focus on Microscopy (FOM) conference will take place in Krakow, Poland. It is the continuation of a yearly conference series presenting the latest innovations in optical microscopy and its application in biology, medicine and the material sciences. Key subjects are the theory and practice of 3D optical imaging, related 3D image processing, and reporting especially on developments in resolution and imaging modalities. The FOM conference also covers the rapidly advancing fluorescence labeling techniques for the confocal and multiphoton 3D imaging of live- biological-specimens. A technical exhibition will be a special feature of this year’s conference in Krakow.

Upcoming topics will cover:
– Confocal and multiphoton-excitation microscopy
Novel illumination and detection strategies
– Fluorescence: new labels, fluorescent proteins, quantum dots, single molecule

– Time-resolved fluorescence: FRET, FRAP, FLIM, FCS

– Coherent non-linear microscopy: SHG, THG, SFG, CARS

– Raman, light scattering microscopy

– Multi-dimensional imaging

– Sub-wavelength resolution: near field microscopy, STED, PALM

– Laser manipulation, ablation and microdissection, photoactivation

– Optical tools in genomics, proteomics, phenomics, cytometry

– Magnetic resonance and X-ray microscopy

– Image processing and visualization

– Live cell and whole tissue imaging

The conference will take place at the Jagiellonian University Auditorium Maximum, ul. Krupnicza 35, in the center of Krakow.

Details for registration, abstract submission, deadlines, etc. will soon be available on:
www.focusonmicroscopy.org

Krakow, Poland, source: pixelio.de

Krakow, Poland (source: pixelio.de)