The Twelfth Frontiers of Electron Microscopy in Materials Science, FEMMS2009, will take place from Sept. 27 – Oct. 2, 2009 at “Huis Ten Bosch” in Sasebo/Nagasaki in Kyushu Island, Japan. FEMMS is an international a biennial symposium series focused on the application of electron microscopy, primarily TEM, in the field of materials science. The conference contains a plenary talk, 9 sessions of invited talks and poster sessions of contributed papers. The sessions cover recent progresses and emerging trends, such as current instrument advances in TEM, SEM, HVEM and detecting systems, ultra-high resolution imaging and analysis, in-situ and ultra-fast analysis, 3-dimensional analysis, and so on. Dr. Akira Tonomura, a world renowned pioneer in the field of electron holography, will give a plenary talk as the distinguished lectureship award winner.